Lothar Rink Selected Research

Zinc

1/2024	Leukemia cells accumulate zinc for oncofusion protein stabilization.
10/2023	Zinc Modulates Glutamine Metabolism in T Cells.
7/2023	Regulation of matrix metalloproteinase-9 during monopoiesis and zinc deficiency by chromatin remodeling.
11/2022	Zinc in Human Health and Infectious Diseases.
8/2022	Zinc supplementation prior to heat shock enhances HSP70 synthesis through HSF1 phosphorylation at serine 326 in human peripheral mononuclear cells.
8/2022	The human long noncoding RNAs CoroMarker, MALAT1, CDR1as, and LINC00460 in whole blood of individuals after controlled short-term exposure with ultrafine metal fume particles at workplace conditions, and in human macrophages in vitro.
2/2022	Zinc Status Impacts the Epidermal Growth Factor Receptor and Downstream Protein Expression in A549 Cells.
1/2022	Zinc deficiency as a possible risk factor for increased susceptibility and severe progression of Corona Virus Disease 19.
1/2022	Rebalancing the unbalanced aged immune system - A special focus on zinc.
12/2021	Retrospective observational study evaluating zinc plasma level in patients undergoing thoracoabdominal aortic aneurysm repair and its correlation with outcome.

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Lothar Rink Research Topics

Disease

22	Infections 12/2023 - 01/2002
14	Inflammation (Inflammations) 08/2022 - 11/2006
12	Neoplasms (Cancer) 01/2024 - 02/2007
12	Autoimmune Diseases (Autoimmune Disease) 10/2023 - 10/2006
5	Respiratory Tract Infections (Respiratory Tract Infection) 11/2022 - 01/2020
5	Septic Shock (Toxic Shock Syndrome) 12/2021 - 03/2006
4	Malnutrition (Nutritional Deficiencies) 11/2022 - 01/2010
3	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 10/2023 - 05/2004
3	Chronic Disease (Chronic Diseases) 11/2022 - 01/2021
3	Cardiovascular Diseases (Cardiovascular Disease) 08/2022 - 09/2014
3	COVID-19 01/2022 - 01/2020
3	Virus Diseases (Viral Diseases) 01/2022 - 02/2007
3	Sepsis (Septicemia) 12/2021 - 11/2006
3	Necrosis 04/2019 - 11/2006
3	Hypersensitivity (Allergy) 08/2017 - 03/2016
3	Diabetes Mellitus 10/2015 - 06/2009
3	Type 2 Diabetes Mellitus (MODY) 09/2014 - 06/2009
2	Leukemia 01/2024 - 11/2010
2	Mycoses (Diseases, Fungus) 12/2023 - 06/2022
2	Malaria 11/2022 - 01/2008
2	Tuberculosis (Tuberculoses) 11/2022 - 01/2008
2	Communicable Diseases (Infectious Diseases) 11/2022 - 01/2017
2	Bronchiolo-Alveolar Adenocarcinoma (Adenocarcinoma, Bronchiolo Alveolar) 02/2022 - 12/2020
2	Pneumonia (Pneumonitis) 12/2021 - 01/2008
2	Lung Injury 07/2020 - 01/2020
2	Atherosclerosis 07/2020 - 09/2014
2	Graft vs Host Disease (Graft-Versus-Host Disease) 12/2018 - 03/2016
2	Asthma (Bronchial Asthma) 09/2018 - 06/2009
2	Rheumatoid Arthritis 06/2009 - 01/2008
1	Hematologic Neoplasms (Hematological Malignancy) 01/2024
1	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 01/2024
1	Acute Promyelocytic Leukemia 01/2024
1	Chromosome Aberrations (Chromosome Abnormalities) 01/2024
1	Pathologic Processes 07/2023
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2023
1	Immune System Diseases (Immune Disorders) 11/2022
1	Carcinogenesis 02/2022
1	Lung Neoplasms (Lung Cancer) 02/2022
1	Peripheral Arterial Disease 12/2021
1	Thoracoabdominal Aortic Aneurysm 12/2021
1	Urinary Tract Infections (Urinary Tract Infection) 12/2021
1	Ageusia (Hypogeusia) 02/2021
1	Anosmia 02/2021
1	Lung Diseases (Lung Disease) 02/2021
1	Obesity 07/2020
1	Cytokine Release Syndrome 07/2020
1	Acute Lung Injury 01/2020
1	Mucositis 04/2019
1	Insulin Resistance 01/2019
1	Body Weight (Weight, Body) 03/2016
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 03/2016
1	Multiple Sclerosis 03/2016
1	Granulomatosis with Polyangiitis (Wegener's Granulomatosis) 03/2016
1	Glomerulonephritis 03/2016
1	Carotid Artery Diseases 11/2015

Drug/Important Bio-Agent (IBA)

46	ZincIBA 01/2024 - 10/2006
6	CytokinesIBA 09/2016 - 01/2002
4	Proteins (Proteins, Gene)FDA Link 01/2024 - 07/2010
3	allicinIBA 12/2023 - 01/2019
3	MicronutrientsIBA 02/2021 - 06/2017
3	Interleukin-6 (Interleukin 6)IBA 04/2019 - 11/2006
3	Insulin (Novolin)FDA Link 01/2019 - 06/2009
3	MetallothioneinIBA 09/2014 - 06/2009
3	SuperantigensIBA 07/2010 - 05/2004
2	Proton Pump InhibitorsIBA 01/2023 - 01/2018
2	ErbB Receptors (EGF Receptor)IBA 02/2022 - 12/2020
2	Interleukin-2 (IL2)IBA 01/2021 - 10/2012
2	InterleukinsIBA 04/2019 - 11/2006
2	zirconium oxide (zirconia)IBA 04/2019 - 02/2016
2	Glucose (Dextrose)FDA LinkGeneric 01/2019 - 01/2008
2	Trace Elements (Biometals)IBA 08/2017 - 03/2016
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2016 - 11/2006
2	Zinc Transporter 8IBA 11/2012 - 06/2009
1	Extracellular Matrix ProteinsIBA 07/2023
1	Matrix Metalloproteinase 9 (Gelatinase B)IBA 07/2023
1	Pantoprazole (Protonix)FDA LinkGeneric 01/2023
1	Omeprazole (Prilosec)FDA LinkGeneric 01/2023
1	HSP70 Heat-Shock Proteins (Heat-Shock Protein 70)IBA 08/2022
1	CopperIBA 08/2022
1	Cadherins (E-Cadherin)IBA 02/2022
1	VaccinesIBA 01/2022
1	InterferonsIBA 02/2021
1	Antiviral Agents (Antivirals)IBA 07/2020
1	Vitamin D FDA LinkGeneric 01/2020
1	TitaniumIBA 04/2019
1	C-Reactive ProteinIBA 01/2019
1	ProteomeIBA 01/2019
1	EnzymesIBA 01/2019
1	Glycated Hemoglobin (Glycosylated Hemoglobin)IBA 01/2019
1	Phosphopyruvate Hydratase (Enolase)IBA 01/2019
1	Polychlorinated Biphenyls (PCBs)IBA 01/2017
1	AutoantibodiesIBA 03/2016
1	AntigensIBA 03/2016
1	lithia disilicateIBA 02/2016
1	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 02/2016
1	zinc-binding protein (zinc binding protein)IBA 11/2015

Therapy/Procedure

6	Therapeutics 10/2023 - 03/2017
1	Critical Care (Surgical Intensive Care) 12/2021
1	Oral Hygiene (Dental Hygiene) 04/2019
1	Cardiopulmonary Bypass (Heart-Lung Bypass) 01/2018